Author

S. Abdullaev

3 papers indexed here

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Open access Sep 2026

Impact of Cytochrome P450 and P-glycoprotein Gene Polymorphisms on the Risk of Hemorrhagic Complications in Older Patients with Non-Valvular Atrial Fibrillation Treated with Rivaroxaban

Background: The administration of direct oral anticoagulants to older adults requires careful risk stratification against a backdrop of polypharmacy and age-related renal function decline. The role of single nucleotide polymorphisms in cytochrome P450 genes and efflux transporters in this context remains a clinically u...

I. Sychev, A. Kondrakhin, S. Abdullaev et al. · Journal of Personalized Medi... · 0 citations

Open access Sep 2026

Pharmacogenetics-Guided De-Escalation of Dual Antiplatelet Therapy Based on CYP2C19 Testing in Patients After Acute Coronary Syndrome: Clinical Outcomes and Cost–Consequence Analysis

No statistically significant differences in bleeding or ischemic events were detected between genotype-guided de-escalation of DAPT based on CYP2C19 testing and standard practice in this trial, and the genotype-guided strategy was associated with a reduction in drug and testing costs.

F. Turaev, S. Abdullaev, K. I. Matrenin et al. · Journal of Clinical Medicine · 0 citations

Open access Sep 2026

Allelic Variants of the DPYD Gene in Russian Patients with Cancer: The Results of Exome Sequencing

The frequency and distribution of common, clinically relevant, and rare DPYD variants in a Russian cohort of patients receiving fluoropyrimidine-containing chemotherapy and the observed allele frequencies with European and East Asian reference populations are compared.

D. Fedorinov, V. Lyadov, M. Lyadova et al. · Genes · 0 citations