Jul 2026
Dihalogenated indoles with antimicrobial activity against C. acnes and polymicrobial biofilms.
It is demonstrated that a dihalogenated indole reduces lipase-associated virulence related phenotypes in C. acnes and suppresses biofilm formation in skin-relevant environments, supporting further investigation of this scaffold as a therapeutic strategy targeting acne-associated microbial physiology.
S. Angulmaduwa, G. G. Roshan Pradeep Ratupaskatiye, Yong-Guy Kim et al.
· Microbial Pathogenesis · 1 citation