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Open access Sep 2026

1,8-CINEOLE ATTENUATES LIPOPOLYSACCHARIDE-INDUCED INFLAMMATORY RESPONSES IN RAW 264.7 MACROPHAGES THROUGH RESTORATION OF ANTIOXIDANT DEFENSE AND SUPPRESSION OF NF-ΚB-ASSOCIATED CYTOKINE SIGNALING

Objectives: This study aimed to evaluate the anti-inflammatory effects of 1,8-cineole (eucalyptol) in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages by assessing inflammatory mediators, antioxidant status, gene expression, and nuclear factor kappa B (NF-κB)-associated cytokine signaling. Methods: RAW 264.7 m...

Avinash Devaraneni, Sulthan Al Rashid, S. B et al. · 0 citations
Open access Sep 2026

IN VITRO EVALUATION OF HESPERIDIN AS A HEPATOPROTECTIVE AGENT AGAINST CYCLOPHOSPHAMIDE-INDUCED OXIDATIVE AND INFLAMMATORY INJURY

Objective: The objective of the study is to investigate the hepatoprotective effects of hesperidin against cyclophosphamide-induced oxidative stress and inflammatory injury in HepG2 cells, with particular emphasis on modulation of the nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) antioxidan...

Gundeti Tharun Reddy, K. Vignesh, J. M. Joy et al. · 0 citations

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