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Sep 2026

The Impact of Anastomotic Leak After Esophagectomy on Long-term Survival in the Modern Era of Management (ALES Study): A Multicenter Cohort Study.

OBJECTIVE To determine the impact of severity of esophageal anastomotic leak (AL), standardized by ECCG grading, on long-term survival within a contemporary multicenter cohort. SUMMARY BACKGROUND DATA Historical evidence suggesting AL is associated with increased recurrence and poor survival is limited by heterogeneo...

Lorenzo Giorgi, Nadia Guidozzi, Riadh Salem et al. · 0 citations
Open access Aug 2026

The role of circulating tumor DNA (ctDNA) to detect minimal residual disease in locally advanced gastroesophageal carcinoma: the BUTTERFLY study

Background Despite advances in perioperative and neoadjuvant strategies, patients with locally advanced gastroesophageal cancers remain at high risk of recurrence after curative intent treatment. No validated biomarkers are available to detect minimal residual disease (MRD) or to guide post-operative risk-adapted manag...

A. Puccini, L. Paracchini, R. Alfieri et al. · 0 citations

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