Early-Life Wheezing and Atopic Burden Are Associated with Treatment-Defined Asthma Severity and Control in School-Age Children: A Two-Center Cross-Sectional Study
Background: Childhood asthma is clinically heterogeneous, yet simple clinical approaches for describing concurrent disease burden are limited. We tested whether a two-axis phenotype matrix—built from early-onset and/or high-burden wheeze and atopic load—is associated cross-sectionally with treatment-defined severity an...