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Open access Oct 2026

Pre-splicing factors associate with UpA-rich RNA and limit flavivirus replication.

RNA affinity purification coupled with mass spectrometry is used to identify diverse host factors that preferentially bind UpA-high RNA sequences, revealing a novel antiviral role for splicing factors, linking their preferential association with UpA-rich RNA to the restriction of UpA-high viruses.

Joyce W. M. van Bree, Kristel Doets, Carmen van de Waterbeemd et al. · 0 citations

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