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Author

S. Bonelli

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Open access Sep 2026

Re-evaluating impaired consciousness in temporal lobe epilepsy: The role of language dominance and network reorganization.

OBJECTIVE Temporal lobe epilepsy (TLE) frequently affects clinically-classified ictal consciousness, which the 2025 International League Against Epilepsy (ILAE) classification operationalizes through clinical assessment of awareness and responsiveness. It remains uncertain whether the spatial lateralization between the...

R. Stepponat, M. Berger, Laurin Schäfer et al. · 0 citations
Open access Aug 2026

Uncovering Individual Language Vulnerability in Epilepsy Through Functional Connectivity Laterality.

BACKGROUND Language processing is organized in brain networks, generally lateralized to the left hemisphere. In clinical routine, task-based functional MRI (fMRI) is the gold standard for non-invasive evaluation of language lateralization. However, standard fMRI does not account for the individual heterogeneity of lang...

R. Stepponat, Mehmet-Salih Yildirim, M. Berger et al. · 0 citations
Open access Aug 2026

Rare genetic variation in adults with surgically treated temporal lobe epilepsy: An exome sequencing study

The results suggest that single‐gene causes are rare in adults with TLE, consistent with previous reports indicating a low diagnostic yield of presurgical genetic testing and further support a predominantly polygenic architecture of TLE.

Antonia P. Pirker, Margot Ernst, Matias Wagner et al. · 0 citations

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