S. C. Chen-Cardenas

Clinical Utilization of CYP17A1 and CYP11B2 in Evaluating Cortisol- and Aldosterone-Producing Adrenal Nodules.

Mild autonomous cortisol secretion (MACS) has been increasingly recognized as a risk factor for cardiometabolic comorbidities and increased mortality. While CYP11B2 immunohistochemistry (IHC) based HISTALDO classification is well established for evaluating primary aldosteronism (PA), the clinical utility of CYP17A1 IHC...