BACKGROUND
Invasive fungal infections are associated with high morbidity and mortality, particularly among immunocompromised and critically ill patients. Antifungal therapy is complicated by substantial pharmacokinetic variability, drug-drug interactions, and narrow therapeutic windows for some agents. Although therape...
J. Cusato, A. Cafaro, S. Cairoli et al.· Therapeutic Drug Monitoring· 0 citations
Sarcopenia is increasingly recognized in pediatric chronic diseases, yet its prevalence and determinants in children with intoxication‐type inborn errors of metabolism (IEM) have never been investigated. This study aimed to evaluate sarcopenia in this population and to investigate associated metabolic alterations. We c...
S. Veraldi, Maria Sole Basso, Giovanna Soglia et al.· Journal of Inherited Metabol...· 0 citations
Recent phase I/II clinical trials have demonstrated that chimeric antigen receptor (CAR) T cells targeting the disialogangliosade GD2 represent a promising therapeutic option for pediatric patients with relapsed or refractory high-risk neuroblastoma (NB). However, incomplete and heterogeneous clinical responses highlig...
Marsha Pellegrino, Simone Vespa, I. Salvatori et al.· Biomarker Research· 0 citations
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