To develop and validate a reverse-phase high-performance liquid chromatography (RP-HPLC) bioanalytical method for quantifying cefpodoxime proxetil (CFP) epimers in human plasma and to integrate metabolite synthesis, hydrolysis kinetics, antibacterial evaluation, in silico toxicity prediction, and analytical sustainabil...
S. Chhajed, H. Chikhale, S. Sonawane et al.· Discover Chemistry· 0 citations
A new line of triazine-benzopyran hybrid compounds, 1,3,5-triazin-2-yl) oxy)-4-methyl-2H- chromen-2- ones, has been developed, synthesized, and physiologically explored as epidermal growth factor receptor (EGFR) inhibitors for cancer treatment. The work used pharmacophore hybridization to increase receptor affinity and...
Abhijit S. Deore, S. Chhajed· Indian Journal of Heterocycl...· 0 citations
This research aimed to demonstrate the activity of several promising benzanilide molecules, showing promising growth-inhibitory cytotoxic actions with increasing concentrations against EGFR in breast cancer.
M. Parab, Pramodkumar P. Gupta, S. Shetty et al.· Biotechnology Notes· 0 citations
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