Author

S. di Martino

3 papers indexed here

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Review Open access Oct 2026

Towards epigenetically informed and biobank-driven precision immunotherapy in melanoma

Cutaneous melanoma (CM) is a highly immunogenic and therapeutically intricate solid tumor, exemplifying the interactions between tumors and the immune system. Despite the significant enhancement in survival rates for patients with advanced melanoma due to immune checkpoint inhibitors (ICIs), numerous patients either ex...

L. Ciuffreda, I. Falcone, C. Sorino et al. · Frontiers in Immunology · 0 citations

Open access Sep 2026

In silico-guided design, synthesis and in vitro evaluation of thiazolo-pyridines targeting SARS-CoV-2 Nsp13.

In the search for novel antiviral agents targeting SARS-CoV-2 non-structural protein 13 (Nsp13), we applied an integrated in silico drug design workflow combining ADME profiling, molecular interaction field analysis, molecular docking and thermodynamic evaluations to identify thiazolo-pyridine derivatives as promising...

R. Bivacqua, Roberta Emmolo, Gianmarco Gualtieri et al. · European journal of medicina... · 0 citations

Open access Sep 2026

Peptide-based therapeutics targeting GPCRs: recent applications in the treatment of metabolic disorders

G protein-coupled receptors are among the largest protein superfamilies in the human genome and are responsible for sensing diverse extracellular signals and mediating them into cellular responses. Owing to their broad range of subunits and downstream effectors regulated by specific ligands, these receptors have been a...

S. di Martino, Maria De Rosa · Frontiers in Pharmacology · 0 citations