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S. Dryer

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Open access Oct 2026

TLR4 signaling cascades leading to increases in albumin permeability, nephrin ectodomain shedding, and apoptosis in MPC‐5 podocytes

Abstract Proteinuria is a cardinal symptom of kidney disease, but common transient proteinurias may reflect a normal physiological response to distant tissue damage or infection. Here we observed that activation of Toll‐like receptor‐4 (TLR4) using the selective agonist CRX572 induced three distinct functional effects...

Eun Young Kim, S. Dryer · 0 citations

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