Author

S. Ergün

2 papers indexed here

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Open access Aug 2026

SPRTN preserves RNA polymerase I transcription under genotoxic drug stress in lung adenocarcinoma

Background Hyperactivated RNA polymerase I (Pol I)-driven ribosomal DNA (rDNA) transcription sustains malignant growth and chemotherapy tolerance in lung adenocarcinoma (LUAD). Genotoxic chemotherapeutics such as doxorubicin and cisplatin preferentially damage rDNA by inducing DNA-protein crosslinks (DPCs), yet how tum...

Mansi Sharma, Srikanth Karnati, S. Ergün et al. · Frontiers in Oncology · 0 citations

Review Open access Sep 2026

Female Reproductive System Assembloids in Health and Disease

In just over a decade, in vitro modeling of the female reproductive tract has advanced from planar monolayers of immortalized cells to self-organizing epithelial organoids and, most recently, to increasingly complex multicellular and multicompartment 3D models, including assembloids that combine organoids with addition...

Mete Hakan Karalök, Burcu Biltekin, Turgay Barut et al. · Cells · 0 citations