Author

S. Fahmy

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Review Open access Jul 2026

Metal–organic framework-based therapeutic strategies for hepatocellular carcinoma: current advances and future perspectives

This review highlights the recent progress in MOF-based nanomedicine for liver cancer treatment specifically HCC, emphasizing targeting strategies that enhance the selective accumulation of MOF nanocarriers in liver tumors, including passive targeting via the enhanced permeability and retention (EPR) effect and active...

Manar T. El-Morsy, A. Elshekh, M. Ghazy et al. · Cancer nanotechnology · 1 citation

Open access Jul 2026

Structure‐Based Design, Synthesis, and Biological Evaluation of Oxadiazole–Morpholine Hybrids as Potent PARP‐1 Inhibitors Inducing Apoptosis in Breast Cancer Cells

Poly(ADP‐ribose) polymerase‐1 (PARP‐1) plays a central role in the repair of DNA single‐strand breaks and represents an established therapeutic target in cancer treatment. In this study, a series of novel oxadiazole–morpholine hybrid compounds was designed and synthesized using a structure‐based drug design approach to...

Nader R Albujuq, Khaled M. Darwish, S. Fahmy et al. · Drug development research (P... · 0 citations