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S. Fukushima

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Open access Sep 2026

Aging-related IgG accumulation promotes skin inflammation.

Aging skin is characterized by wrinkles, loss of elasticity, and impaired barrier function, largely driven by alterations in dermal fibroblasts and extracellular matrix remodeling. Chronic, age-related inflammation, called inflammaging, is a central activity underlying these changes. Immunoglobulin G (IgG) has recently...

Takehisa Suzuki, Haruki Horiguchi, Shuji Yamamura et al. · 0 citations

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