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Author

S. Ghafouri-Fard

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Open access Sep 2026

Pro-inflammatory and autophagic pathways in lung cancer: dysregulation of key genes ADINR, C/EBPα, CHAST, ATG5, IL-1B, and DICER1-AS1

Purpose Lung cancer is the second most prevalent malignancy in both sexes and remains the leading cause of cancer-related mortality. This study aimed to evaluate the expression profile of selected Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling-related genes and long non-coding RNAs (ln...

A. Sayad, Mahsa Mousazadeh, Mohammad Amin Hahem Nejad et al. · 0 citations
Open access Sep 2026

Identification of PANoptosis-related lncRNAs in colorectal cancer: Bioinformatic and experimental insights into LMNTD2-AS1, ASMTL-AS1 and SNHG12.

PANoptosis is a newly discovered form of programmed cell death. Accumulating studies confirmed that long non-coding RNAs (lncRNAs) play crucial role in colorectal cancer (CRC) progression. However, the role of PANoptosis-related lncRNAs in CRC has not yet been elucidated. In the current study, we used a bioinformatics...

Mahla Sanati, Solat Eslami, Zahra Fazeli et al. · 0 citations
Open access Sep 2026

Downregulation of prenylation machinery genes in peripheral blood of patients with Parkinson’s disease: A pilot study

The findings support dysregulation of the protein prenylation machinery as a potentially informative molecular feature of Parkinson’s disease; however, the contribution of medication exposure and blood-cell composition could not be fully assessed, and independent external validation is required before clinical biomarke...

Mohammad Jalal Tabatabaie, Solat Eslami, Atefe Abak et al. · 0 citations
Open access Jul 2026

Discovery of a prognostic two-lncRNA panel correlated with immune-associated transcripts for forecasting overall survival in pancreatic cancer.

The presented findings offer novel insights into the correlation of immune-related lncRNAs with pancreatic cancer progression and provide a foundation for future risk stratification modeling.

Hajar Eftekhari, Arash Safarzadeh, Emad Babakhanzadeh et al. · 0 citations
Open access Aug 2026

Whole Exome Sequencing Unveils Novel Pathogenic Variants in an Iranian Cohort with Retinal Dystrophies: Implications for Genetic Diagnosis and Counseling.

The findings have the potential to enhance genetic counseling and improve the classification of subtypes in RD, and demonstrate the utility of WES in the molecular diagnosis of retinal dystrophies, highlighting the importance of functional validation of newly identified variants.

elham alimoradi, Arash Salmaninejad, Parham Nejati et al. · 0 citations
Review Open access Aug 2026

Molecular and clinical heterogeneity in an Iranian case series of Joubert syndrome

This study expands the mutational landscape of JS in the Iranian population and underscores the utility of WES as a first-tier diagnostic tool for JS and related ciliopathies.

Sheyda Khalilian, Mohadeseh Fathi, Zahra Farbood et al. · 0 citations

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