Author

S. Grottoli

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Open access Sep 2026

Insulin Tolerance Test in Adult GH Deficiency: An Exploratory Study Deriving BMI-Dependent Cut-Offs Using a Clinical Reference Standard

Background: The diagnosis of adult growth hormone (GH) deficiency (GHD) relies on demonstrating a reduced GH response to stimulation tests. Excess body weight, an increasingly prevalent condition, is associated with a blunted GH response to all types of stimulation tests. Therefore, establishing body mass index (BMI)-d...

D. Cuboni, F. Mocellini, M. Sibilla et al. · Biomedicines · 0 citations

Review Open access Aug 2026

EP1029 - ECE_1026 - Serum neurofilament light chain: a candidate biomarker of neuroaxonal injury in patients with dysnatremia, associated with functional outcomes and mortality

High sNfL levels were associated with worse cognitive performance and muscle strength, independent of sodium levels and other potential confounders, and could serve as a novel biomarker of neuroaxonal injury in patients with hyponatremia, correlated with functional outcomes and mortality.

F. Bioletto, D. Cuboni, E. Varaldo et al. · European Journal of Endocrin... · 0 citations

Open access Aug 2026

CB03 Evaluation of trabecular bone score as a predictor of incident fragility fractures in patients with acromegaly: an international retrospective cohort study

In patients with acromegaly, TBS is associated with prevalent but not incident vertebral fractures, and periodic vertebral morphometric assessment remains essential for early fracture detection and fracture risk stratification.

F. Bioletto, M. Sibilla, M. Barale et al. · European Journal of Endocrin... · 0 citations