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Author

S. Haas

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Open access Aug 2026

The cortical microenvironment drives early immune organization and controls early osteoclastogenesis in bone healing

Bone regeneration is a complex, tightly regulated process involving coordinated interactions of immune and stromal cells. Early phases of healing rely on the timely clearance of debris, a task primarily carried out by macrophages and osteoclasts. However, the sequence of events leading to the presence of osteoclasts at...

Anne Noom, H. Oktay, Duncan M. Morgan et al. · 0 citations
Open access Aug 2026

Perturb-seq identifies co-regulated gene programs shaping hematopoietic stem and progenitor cell function

Perturbation-derived co-regulation programs are established as an interpretable framework for linking genetic regulators, cell-biological processes and stem-cell-associated phenotypes by decomposing gene expression data from functional and clinical studies into program activity.

Joseph S. Bowness, Aina Bernal Martínez, Jan Bařinka et al. · 0 citations

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