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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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S. Hägg

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Open access Aug 2026

A generalized approach for estimating the Pace of Aging

Abstract Background Quantifying the rate of aging is essential for understanding age-related physiological decline and predicting late-life outcomes. The Pace of Aging (PoA) framework addresses this by modeling longitudinal changes across multiple biomarkers. However, the original Dunedin PoA assigns equal weight to al...

Marije H. Sluiskes, J. Deelen, H. Putter et al. · 0 citations
Open access Sep 2026

Integrative prediction of Alzheimer's disease and related dementias using multi‐omics aging clocks and genetic data

Abstract INTRODUCTION We tested whether combining Alzheimer's disease and related dementias (ADRD) polygenic risk scores (PRS) with biological aging markers improves ADRD risk prediction. METHODS In 16,215 UK Biobank (UKB) participants free of ADRD at baseline (median follow‐up: 10.08 years), 397 incident diagnoses wer...

S. Mostafaei, Karolina Gustavsson, Hampus Hagelin et al. · 0 citations

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