PURPOSE
TAPUR is a phase II basket trial evaluating the antitumor activity of commercially available targeted agents in patients with advanced cancer and genomic alterations. Results of two cohorts of patients with various solid tumors with FGFR1 or FGFR2 alterations treated with sunitinib are reported.
METHODS
Eligi...
Gordan Srkalovic, M. Rothe, E. Garrett-Mayer et al.· JCO Precision Oncology· 0 citations
A Bayesian discretized survival time inference framework in which individualized predictions from potentially multiple external sources are integrated through a formulation based on Kullback-Leibler divergence, yielding informative priors is developed.
Yena Jeon, Yunxiang Huang, H. Kim et al.· 0 citations
It is argued that achieving the potential of AI in oncology clinical trials will require rigorous prospective validation, harmonized regulatory standards, and coordination among clinicians, trialists, regulators, industry and patients.
Andrea Villa, A. Eadie, David Synnott et al.· Nature Reviews Clinical Onco...· 0 citations
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