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Author

S. Hippenmeyer

2 papers indexed here

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Open access Aug 2026

Temporal uncoupling of radial glia lineage progression in cortical organoids

It is found that RGPs exhibit a high level of plasticity in proliferative potential in organoids rather than strict temporally stereotyped lineage progression as observed in vivo, indicating that missing non-cell-autonomous niche cues are essential for faithful temporal control of cortical lineage progression.

Melissa Stouffer, Osvaldo A. Miranda, F. Pauler et al. · 2 citations
Open access Sep 2026

A human transcriptomic deletion links cortical expansion and cancer

Analysis of RNA-sequencing data from nine iPSC-derived cell types and dozens of human transcriptomic conserved deletions suggests that evolution of HMMR splicing in humans increased plasticity in cell division, potentially leading to tradeoffs between advantageous effects on brain development and deleterious effects on...

Alexander L. Starr, A. Villalba, Jenna Rever et al. · 0 citations

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