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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

S. Holmboe

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Open access Sep 2026

Circulating matrix GLA protein during puberty in healthy and central precocious puberty children

Objective Matrix GLA protein (MGP) is involved in the regulation of extracellular matrix mineralisation, including bone formation. The peripubertal years are critical for linear growth and acquisition of bone mass. Emerging evidence suggests that plasma concentrations of dephosphorylated undercarboxylated MGP (dp-ucMGP...

Maria Bentz Damholt, S. Holmboe, J. H. Petersen et al. · 0 citations
Open access Aug 2026

CYP19A1 variation in healthy children: associations with breast development and pubertal gynecomastia

Background CYP19A1 encodes aromatase, the enzyme converting androgens to estrogens, thereby influencing breast tissue development in healthy children. Objective To examine associations between CYP19A1 single nucleotide polymorphisms (SNPs) and circulating estradiol (E2) and testosterone (T), the E2/T ratio and age at t...

Veronica L R Groendahl, S. Holmboe, A. Busch et al. · 0 citations

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