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Author

S. Hsu

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Review Open access Sep 2026

Tied to Work: Topologically Knotted SPOUT Methyltransferases and UCH Deubiquitinases in Cellular Biochemistry

Topologically knotted proteins are emerging as functional elements of the proteome rather than structural curiosities. Among the recurring protein knot types, the 31 trefoil, 52 Gordian and 71 septoil knots provide useful models for understanding how topology may reshape catalysis, substrate recognition, folding and me...

S. Hsu · 0 citations
Open access Jul 2026

Substrate biasing in UCHL5 proteoforms

The molecular basis for substrate selectivity in a deubiquitinating enzyme is described, an unexplored area in the enzymes that counteract ubiquitin E3 ligases, an unexplored area in the enzymes that counteract ubiquitin E3 ligases.

Rishi S. Patel, Nipuni M. Pannala, Chih-Hsuan Lai et al. · 0 citations
Open access Jan 2026

Characterization and Evaluation of the Pathogenicity of a Novel Alpha Family Chaperone‐Usher Pilus Present on Porcine Enterotoxigenic Escherichia coli

The results indicate that Taiwan porcine ETECs carried AMR genes and alternative CU pathway pilus, and the role of the CS33 pilus on the pathogenicity or virulence of the pathogen requires further investigation and surveillance.

Yi-Fang Lai, Yen-Chen Chang, Wei-Ting Lee et al. · 0 citations

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