Author

S. Huntley

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Sep 2026

The Orphan Histidine Kinase TodK Influences Myxococcus xanthus Multicellular Development by Inactivating the CRP/Fnr Homolog, MrpC.

It is found that loss of TodK produces distinct developmental phenotypes that vary with environmental conditions, and quantitative phenotyping approaches can reveal biologically meaningful functions for orphan histidine kinases whose mutant phenotypes might otherwise appear subtle.

Christopher Mataczynski, Maike M. Glaser, S. Huntley et al. · Molecular Microbiology · 0 citations

Open access Jul 2026

The orphan histidine kinase TodK controls Myxococcus xanthus biofilm development by inactivating the CRP/Fnr homolog, MrpC

Findings establish TodK as a modulator of developmental progression and demonstrate how quantitative phenotyping approaches can reveal biologically meaningful functions for orphan histidine kinases whose mutant phenotypes might otherwise appear subtle.

Christopher Mataczynski, Maike M. Glaser, S. Huntley et al. · bioRxiv · 0 citations