S. Kalinichenko

IMMUNE IMPRINTING IN INFLUENZA: CELLULAR MECHANISMS, CLINICAL SIGNIFICANCE, AND PROSPECTS FOR NEXT – GENERATION VACCINE DEVELOPMENT

Influenza viruses remain a major cause of seasonal morbidity and mortality worldwide, while the effectiveness of current influenza vaccines depends not only on the antigenic match between vaccine and circulating strains but also on an individual’s immunological history. One of the key mechanisms shaping both infection-...