Author

S. Kalivendi

2 papers indexed here

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Aug 2026

USP13-SKP2-P57/kip2 Axis Mediates Spautin-1 Induced Transcriptional Upregulation of NURR1: Implications for NURR1 Mediated Neurotrophic Activity.

The progressive loss of midbrain dopamine neurons leading to motor deficits is the primary cause of Parkinson's disease (PD). Emerging reports on the role of NURR1 in the differentiation and maintenance of dopamine neurons; the association of reduced levels/familial mutants of NURR1 in PD subjects makes it a promising...

Anna Edward, Srinivas N. Puttapaka, Aravind Vulli et al. · ACS Chemical Neuroscience · 0 citations

2026

Identification of 2,4-dihydroxy-azaflavanone as an allosteric activator of SIRT1 and its potential role in cellular models of Parkinson's disease.

This chapter outlines a detailed, multi-layered methodological framework for assessing the allosteric activation of SIRT1 by 2,4-dihydroxy-azaflavanone and its downstream effects in a cellular models of PD.

Chitrakshi Pant, Vidya Jyothi Alli, Genji Sukumar et al. · Methods in Enzymology · 0 citations