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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

S. Karagiannis

h-index 7 View on Semantic Scholar

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Open access Sep 2026

The phenotypic heterogeneity of tumor-derived cells in the bloodstream of pancreatic cancer patients

These findings provide a comprehensive characterization of CTCs and CTACs in PC using a multiplex biomarker panel associated with calcium signaling and immune checkpoint pathways, highlighting the pronounced heterogeneity and potential clinical relevance of these circulating cell populations.

Chrysoula Tagari, Karolina Mangani, Michael Gogolides et al. · 0 citations
Open access Aug 2026

Tumor-infiltrating B cells evolve towards interferon-rich trajectories aligned with immunotherapy in melanoma

Melanoma-infiltrating B cells follow class-switched differentiation trajectories culminating in IFN signaling, atypical antibody expressing states that persist or emerge after immunotherapy, aligning dynamic B cell evolution and atypical lineage traits with immunotherapy.

K. Stoker, R. Laddach, Lucy Booth et al. · 0 citations
Review Open access Aug 2026

Developing next-generation antibody-drug conjugates for breast cancer drug delivery: hurdles and advances in the clinic.

This review synthesizes literature spanning 1990-2026 on advances in ADC design and their clinical and translational implementation in breast cancer to support reframing antigen selection as a system-level challenge, supported by delivery-focused engineering, precision-medicine-driven trial design, and adaptive methodo...

Callum Chapman, A. Cheung, G. B. Armstrong et al. · 0 citations

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