Open access
Sep 2026
A novel sulfatide analog recognized by human iNKT cells enhances polyfunctional antigen-specific CD8+ T cell responses
Invariant natural killer T (iNKT) cells are CD1d‐restricted T cells that recognize lipid antigens. Studies of analogs of a prototypic iNKT cell antigen, α‐galactosylceramide (α‐GalCer), have shown that ceramide structure affects the activities of mouse iNKT cells recognizing the antigen. However, the impact of antigen...
Ayaka Hara, Julia DiSapio, Morgan Coombs et al.
· European Journal of Immunolo... · 0 citations