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Author

S. Kigar

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Open access Sep 2026

206. Adaptive immune system changes related to stress and depression: clinical and preclinical insights

Abstract Background A challenge for developing new major depressive disorder (MDD) treatments is understanding how non-heritable risk factors like stress alter biological processes. We previously used preclinical animal models to demonstrate chronic psychosocial stress reorganizes the peripheral and meningeal immune mi...

S. Kigar, X. Shen, S. White et al. · 0 citations
Open access Jul 2026

Blood-based immunophenotyping of T cell profiles in patients with neurodegenerative disorders.

Examination of blood-based T-cell profiles across a range of neurodegenerative dementias provides evidence that T-cell dysregulation is not unified in patients with neurodegenerative diseases and observes different involvement across different dementia types establishing adaptive immunity as a key contributor to diseas...

Frederika Malichova, P. Swann, S. Kigar et al. · 0 citations

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