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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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S. Kirubakaran

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Open access Aug 2026

Rewiring mitotic checkpoint control via Mps1 inhibition overcomes DNA repair-mediated resistance in glioblastoma

G17, a small molecule that selectively inhibits monopolar spindle 1 (Mps1), the central kinase controlling SAC signaling, is developed and provided pharmacological evidence that disrupting SAC signaling can expose a DNA repair vulnerability in glioblastoma.

Gaurav Rai, S. Kirubakaran · 0 citations

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