Review
Open access
Jun 2026
Why antibody isotype matters for immunotherapy
Abstract Monoclonal antibodies (mAbs), engineered to recognize disease-associated antigens, are central to cancer immunotherapy due to their ability to block or eliminate malignant cells by engaging immune effector mechanisms. Yet many tumors evade or suppress these responses, limiting durable clinical benefit and high...
S. Kleinau
· Antibody Therapeutics · 0 citations