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S. Kozhakhmetov

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6 papers indexed here

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Open access Oct 2026

Suicide mortality in Kazakhstan from 2012 to 2024: temporal trends, demographic inequalities, and regional variation

Despite some recent declines, suicides remain a major public health issue in Kazakhstan, with rates persistently above global benchmarks. This study provides the first integrated characterization of temporal trends, demographic characteristics, and regional distribution of suicide mortality in Kazakhstan. Th...

A. Kossumov, T. Zhakupova, N. Imambayeva et al. · 0 citations
Open access Sep 2026

Cervicovaginal Virome Restructuring Associated with HPV Status, Bacterial Dysbiosis, and Cervical Cytological Abnormalities

The cervicovaginal virome remains poorly characterized in relation to human papillomavirus (HPV) infection and bacterial community structure. We performed shotgun metagenomic sequencing of 311 cervicovaginal specimens from a Kazakhstani cohort spanning seven groups defined by HPV status and cervical cytology. Viral com...

A. Kushugulova, N. Kamzayeva, S. Kozhakhmetov et al. · 0 citations
Open access Sep 2026

Cervicovaginal microbiome alterations across HPV infection

Findings indicate that oncogenic potential and dysbiosis severity are not aligned, and that CST type modifies HPV–microbiome interactions.

Laura Chulenbayeva, A. Rakhmankulova, N. Kamzayeva et al. · 0 citations
Open access Sep 2026

Targeted long-read eukaryotic profiling of human stool by broad-range 18S–28S rRNA gene amplicon sequencing on Oxford Nanopore Technologies: a proof-of-concept study

The gut eukaryome, comprising the protists and fungi that fall within the strict definition of the microbiota together with the macroscopic helminths and arthropods that lie outside it, is under-detected by clinical microscopy and by short-read 16S/18S sequencing, yet is increasingly implicated in inflammatory and au...

Ruslan Kalendar, A. Daniyarov, Ulykbek Kairov et al. · 0 citations
Open access Jul 2026

Multi-kingdom cervical microbiome structure in health and dysbiosis: a cross-sectional study from Kazakhstan

Introduction The cervicovaginal microbiome is a key determinant of reproductive health. Its multi-kingdom structure and ecological interactions remain insufficiently characterized across diverse populations. This study aimed to define the composition and cross-kingdom dynamics of the cervical microbiome in women withou...

A. Rakhmankulova, S. Kozhakhmetov, A. Kovenskiy et al. · 0 citations
Review Open access Jul 2026

Reproducible Gut Microbiome Alterations in Major Depressive Disorder: A Systematic Review of Taxonomic and Functional Findings

Current evidence suggests that functional gut microbiome dysregulation may represent a more reproducible biological feature of MDD than isolated taxonomic alterations alone, and large-scale longitudinal multi-omics studies using standardized methodologies are required.

Gulshat Dalibayeva, M. Goremykina, S. Kozhakhmetov et al. · 0 citations

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