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S. Lai

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Open access Aug 2026

Glyoxalase 1 Regulates Methylglyoxal-Derived Nucleic Acid Adduct Burden

It is found that an elevated CEdG adduct burden is associated with increased DNA strand breaks, whereas increased CEG modifications are associated with reduced translational efficiency and mechanistically link metabolic stress-derived chemical lesions to genome instability and translational dysfunction.

Alana Battad, Francisco Núñez, S. Lai et al. · 0 citations

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