The findings provide biological insights that may inform targetable, lipid-oriented nutritional and/or pharmacological strategies to modulate foetal growth and development, with the goal of optimising clinical outcomes for both mother and child.
MPXV infection reprograms host lipid metabolism and exosome composition, with HIV co-infection amplifying inflammatory, metabolic, and trafficking disruptions and link systemic lipid dysregulation to exosome-mediated immunomodulation and identify potential targets for host-directed interventions.
Siqi Yong, Jiaying Zhang, He Tian et al.· i Medicina· 0 citations
A senescent-like MuSC population emerging in acute injury induced muscle regeneration is defined and definitive evidence to demonstrate the positive role of these cells in enhancing muscle repair via their robust secretory phenotypes and inter-cellular communicative capacity is provided.
Xing-Yuan Liu, Ying-Kun Zhang, Yang Li et al.· bioRxiv· 0 citations
Elevated RCII levels were significantly elevated in ACPA-negative RA, ACPA-positive RA, undifferentiated inflammatory arthritis, dermatomyositis, and systemic lupus erythematosus compared with HCs, with the highest levels observed in ACPA-negative RA.
