Author

S. Lancellotti

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Review

cen-The expanded universe of thrombin: a comprehensive review of its hemostasis-independent roles and structure-function relationships

M. Sacco, S. Lancellotti, Antonietta Ferretti et al. · 0 citations

Review Open access Aug 2026

The expanded universe of thrombin: a comprehensive review of its hemostasis-independent roles and structure-function relationships

The molecular basis of thrombin’s versatility is explored, focusing on its allosteric regulation by sodium ions, its two anion-binding exosites, and its primary signaling mechanism via protease-activated receptors.

M. Sacco, S. Lancellotti, Antonietta Ferretti et al. · Bleeding Thrombosis and Vasc... · 0 citations