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S. Laranjo

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Open access Aug 2026

Calcium-mediated force–interval relationship drives post-extrasystolic potentiation in premature ventricular complexes: a computational study

Premature ventricular complexes (PVCs) are common cardiac arrhythmias that can lead to cardiomyopathy when frequent. Post-extrasystolic potentiation (PESP), which is the transient increase in contractility following a PVC, may serve as a predictive marker for heart failure risk; yet, the underlying calcium-mediated mec...

S. Vossen, N. van Osta, G. Lourenço et al. · 0 citations

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