Asymptomatic SARS-CoV-2 infection was a driving force of the COVID-19 pandemic, acting as a silent transmitter of the virus. The question of whether asymptomatic immunity differs from symptomatic immunity remains, as existing studies fail to recruit ‘well-defined’ asymptomatic individuals. Here, we conducted a lo...
Hannah J. Jackson, Georgina Hopkins, Nancy Gomez et al.· Journal of Clinical Immunolo...· 0 citations
Using transgenic 3xTg-AD mice, systemic infection with the β-herpesvirus murine cytomegalovirus (MCMV) accelerates the development of cognitive decline, tauopathy, and synaptic loss in the hippocampus, all of which are key features of AD.
M. Marsden, J. E. McLaren, Ryan J. Bevan et al.· bioRxiv· 3 citations
Infections have long been implicated as causative factors in Alzheimer's disease (AD). Multiple studies have further suggested a key role for herpesviruses, such as cytomegalovirus (CMV). Using transgenic 3xTg-AD mice, we demonstrate that systemic infection with the β-herpesvirus murine CMV (MCMV) accelerates the devel...
M. Marsden, J. McLaren, Ryan J Bevan et al.· Brain : a journal of neurolo...· 0 citations
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