Open access
Aug 2026
Metabolic signatures and machine learning identify gut-liver-heart axis dysfunction as a potential link to major adverse cardiovascular events in coronary artery disease
Dysregulated linoleic acid oxidation, altered PPAR signaling, and disturbed primary bile acid-FGF19 metabolism may represent key metabolic pathways associated with MACE susceptibility and hold significant promise for refining cardiovascular risk stratification and guiding targeted preventive interventions.
Min-Qing Lin, Chun-Ka Wong, K. Au et al.
· Cardiovascular Diabetology · 0 citations