Author

S. Libertini

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Open access Jul 2026

SACF and GILA for in vitro transformation assessment of CRISPR/Cas9-edited cell therapy candidates: a multi-site study.

Data establish multi-site reproducibility of SACF and GILA in the MCF10A-PTPN12 model evaluated here and support their use as animal-free, development-stage characterization tools contributing to tumorigenicity evidence generation.

Lena Dorsheimer, J. Ferreira, Bojing Wang et al. · Gene Therapy · 0 citations