Alzheimer’s Disease DNA Methylation Index (AD-DMI) and its Association with Late-Life Cognitive Function
The AD DNA Methylation Index (AD-DMI), a brain-derived risk index constructed from 100 CpG sites identified by elastic-net logistic regression of methylation data from postmortem dorsolateral prefrontal cortex tissue, provides a biologically grounded framework for linking disease-relevant methylation changes with cogni...