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S. M. Krißmer

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Open access Aug 2026

Vitamin C enhances cytotoxicity of CAR-and εTRuC-engineered γδ T cells and modulates Ca2+, NFAT, NF-κB and ERK signaling in human γδ T cells

γδ T cells have raised interest as effector cells in cancer immunotherapy, due to their broad and HLA-independent reactivity towards multiple tumor entities. Despite promising ongoing clinical studies, there is a need to improve the effector function and thereby the efficacy of γδ T cells. In addition to its role as an...

M. Zarobkiewicz, Lin Ma, Claudia Juraske et al. · 0 citations
Open access Jul 2026

Coding agents author interpretable single-cell embedding models from the literature

C coding agents can author single-cell embedding models directly from the literature, which are competitive in biological quality with conventional, foundation-model, and program-informed baselines, batch-robust by construction and reproducible across runs, complementing data-driven embeddings.

Niklas Brunn, S. M. Krißmer, Maximilian Frosch et al. · 0 citations

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