Open access
Sep 2026
PAX3-SIX2 muscle stem cell heterogeneity drives muscle-specific repair dynamics diversification
It is established that PAX3-SIX2 expression correlates with distinct MuSCs behavior, influencing regeneration rates in a muscle-type-dependent context, and it is suggested that PAX3-SIX2 heterogeneity could be leveraged for targeted therapeutic strategies in muscle-wasting diseases.
Virginia Zoglio, Sarah Chebouti, Fayez Issa et al.
· Science Advances · 0 citations