Author

S. Mantena

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Open access Jul 2026

TCR germline diversity reveals evidence of natural selection on variable and joining alpha chain genes 2250859

T cell receptors (TCRs) orchestrate T cell mediated immunity. While the somatic diversification of TCRs has been extensively studied, inherited genetic diversity in the TCR V, D, and J genes has remained poorly characterized due to the complex, repetitive nature of the TCR loci. As a result, the contribution of g...

S. Mantena, Ali Akbari, S. Raychaudhuri · Journal of Immunology · 0 citations