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Author

S. McFarland

2 papers indexed here

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Oct 2026

Homoleptic oligothienyl-substituted bis(terpyridine) Ir(III) and Ru(II) complexes: synthesis, photophysics, and anticancer and antimicrobial photodynamic therapeutic effects.

In vitro PDT studies demonstrated strong photocytotoxicity under normoxia and hypoxia towards SKMEL28 melanoma cells, with Ir(4T-tpy)2 emerging as the most promising PDT agent among these four complexes, surpassing that of the most commonly used antimicrobial photosensitizers.

Kalara D. Gamage, Zi-Lun Lian, Giulia Kassab et al. · 0 citations
Open access Sep 2026

Electrophilic aromatic halogenation of perylenequinones: a strategy to improve photodynamic properties.

Halogen substitution is a widely used strategy in medicinal chemistry to modulate the physicochemical and biological properties of drug candidates. Here, we report the electrophilic aromatic halogenation of two fungal perylenequinones, ent-shiraiachrome A (1) and hypocrellin B (2), using N-halosuccinimides, where the r...

Reema A. Al-Qiam, Ge Shi, C. Pearce et al. · 0 citations

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