Author

S. Meinke

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Open access Jul 2026

Extracellular vesicle secretome from mesenchymal stromal cells prevents post-ischemic heart failure by targeting cardiac fibrosis.

Myocardial ischemia-reperfusion (MIR) injury drives adverse remodeling and heart failure after ST-elevation myocardial infarction (STEMI), yet no therapy directly targets the fibrotic response. Here, we developed a good manufacturing practice-compatible extracellular vesicle (EV)-enriched secretome from bone marrow mes...

Karl-Henrik Grinnemo, Ken Braesch-Andersen, Johan O. Wedin et al. · Cell Stem Cell · 1 citation

Open access Aug 2026

Oncolytic HSV1716 attenuates tumor-killing activity of infected primary NK cells

Oncolytic herpes simplex virus type-1 (HSV1)–based therapies engage innate immune responses, including natural killer (NK) cells, which are regarded as antiviral effector cells that eliminate virus-infected tumor targets. In this study, we examined interactions between the HSV1–derived oncolytic virus HSV1716 and prima...

K. Susek, D. Holla, C. Marsal et al. · Frontiers in Immunology · 0 citations