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S. Mendiratta

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Open access Oct 2026

A single epigenetic repressor controls opposing developmental tempos in human neural and cranial neural crest lineages

The precise timing of lineage specification is essential for embryonic development, yet the epigenetic mechanisms enforcing human developmental tempo remain poorly understood1,2. Heterozygous loss-of-function variants in ZNF462 cause Weiss-Kruszka syndrome (WKS), a pleiotropic disorder characterized by neurodevelopment...

Zeynep Eda Atmaca Duran, Marcella Birtele, S. Mendiratta et al. · 0 citations

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