Author

S. Nakagawa

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Open access Sep 2026

Vitamin D3 Attenuates Delirium-Like Cognitive Impairment in a Postoperative Mouse Model.

Delirium is an acute neurocognitive impairment triggered by physiological stressors such as medical illness, surgery, or medication use. Although often transient, it is associated with adverse clinical outcomes. Current management primarily relies on nonpharmacological or symptomatic approaches; however, their effectiv...

Kyoka Nakatomi, Koki Okawa, Y. Shigetsura et al. · Biological and Pharmaceutica... · 0 citations

Review Open access Sep 2026

240. Impact of early pharmacotherapy on delirium symptoms following acute stroke in older patients

Abstract Background Post-stroke delirium occurs in approximately 24–43% of patients and is associated with reduced adherence to acute treatment and rehabilitation, ultimately worsening functional outcomes. Preventive management has received increasing attention, and several studies in intensive care settings have demon...

Y. Shigetsura, Y. Miyoshi, D. Hira et al. · International Journal of Neu... · 0 citations

Open access Jul 2026

Complexation of teicoplanin and sulfobutylether-β-cyclodextrin: experimental and theoretical insights into the potential relevance of their molecular interaction to teicoplanin pharmacokinetics.

The results collectively indicate that the direct molecular interaction, whereby the hydrophobic cavity of SBE-β-CD encapsulates most of the hydrophobic side chain of TEIC, can reduce TEIC protein binding and may consequently affect its pharmacokinetics.

Y. Yamada, S. Nakagawa, N. Yoshikawa et al. · International journal of pha... · 0 citations