S. Nakken

DNA-Based Biomarkers as Predictors of Carboplatin Response in Neoadjuvant Treatment for Hormone Receptor Positive and Triple-Negative Breast Cancer.

PURPOSE This prospective, randomized neoadjuvant study evaluated DNA-based biomarkers to identify breast cancer patients most likely to benefit from carboplatin (Cb). While Cb improves outcomes in triple-negative breast cancer (TNBC), responses vary, and its role in aggressive hormone receptor-positive breast cancer (H...

Immune-cell depleted diffuse large B-cell lymphomas have reduced expression of MHC class I

Assessing clinical decision support system tools in precision oncology: piloting ring testing

An international ring test documenting CDSS usage, performance, and manual interpretation revealed clinically relevant discrepancies between laboratories and interpreters, underscoring the need for structured external quality assessment schemes for CDSS tools in addition to the existing laboratory workflow schemes.