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Review Open access Oct 2026

Mitochondrial dysfunction and inflammaging: a mechanistic bridge between bioenergetic failure and senescence.

Ageing is characterized by a progressive decline in mitochondrial integrity that extends beyond impaired energy production to include redox imbalance, defective quality control, altered organelle dynamics, and persistent inflammatory signalling. This review examines mitochondrial dysfunction as a mechanistic bridge lin...

S. Nesci, Cristina Algieri · 0 citations
Open access Oct 2026

Phytochemicals differentially modulate mitochondrial bioenergetics: roles of F1FO-ATPase, respiratory complexes, and mPTP opening.

Phytochemicals can modulate mitochondrial function, but their specific actions on bioenergetic pathways are not fully defined. Here, isolated mitochondria were exposed to three phytocompounds, S-allyl cysteine (SAC), benzyl isothiocyanate (BITC), and epicatechin (EPC), and key mitochondrial parameters were assessed, in...

Antonia Cugliari, Cristina Algieri, P. A. Glogowski et al. · 0 citations

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