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Author

S. Novello

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Open access Sep 2026

Osimertinib in advanced non-small cell lung cancer (NSCLC) harboring different EGFR uncommon variants: real-world data from the Italian biomarker ATLAS database

Osimertinib exhibited meaningful differences in efficacy and resistance mechanisms across distinct ucEGFR mut, and ex19 delins showed comparable survival outcomes and resistance patterns to classical ex19 deletions, albeit with heterogeneous osimertinib sensitivity depending on the deletion–insertion starting codon.

G. Farinea, A. Mogavero, A. Vitale et al. · 0 citations
Open access Jul 2026

Germline determinants of risk and molecular subtype in young-onset lung cancer

A complex germline architecture underlying susceptibility and molecular subtype in young-onset lung cancer is delineated, consistent with additive risk from rare and common variants.

J. LoPiccolo, Ryan L. Collins, Noah Fields et al. · 0 citations

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